So why does a can of Coke make you feel so gooood?
They took the cocaine out almost a hundred years ago.
You know why? It was redundant:
First 10 minutes: 10 teaspoons of sugar hit your system. (100% of your recommended daily intake.) You don’t immediately vomit from the overwhelming sweetness because phosphoric acid cuts the flavor allowing you to keep it down.
20 minutes: Your blood sugar spikes, causing an insulin burst. Your liver responds to this by turning any sugar it can get its hands on into fat. (There’s plenty of that at this particular moment)
40 minutes: Caffeine absorption is complete. Your pupils dilate, your blood pressure rises, as a response your livers dumps more sugar into your bloodstream. The adenosine receptors in your brain are now blocked preventing drowsiness.
45 minutes: Your body ups your dopamine production stimulating the pleasure centers of your brain. This is physically the same way heroin works, by the way.
>60 minutes: The phosphoric acid binds calcium, magnesium and zinc in your lower intestine, providing a further boost in metabolism. This is compounded by high doses of sugar and artificial sweeteners also increasing the urinary excretion of calcium.
>60 Minutes: The caffeine’s diuretic properties come into play. (It makes you have to pee.) It is now assured that you’ll evacuate the bonded calcium, magnesium and zinc that was headed to your bones as well as sodium, electrolyte and water.
>60 minutes: As the rave inside of you dies down you’ll start to have a sugar crash. You may become irritable and/or sluggish. You’ve also now, literally, pissed away all the water that was in the Coke. But not before infusing it with valuable nutrients your body could have used for things like even having the ability to hydrate your system or build strong bones and teeth.
This will all be followed by a caffeine crash in the next few hours and you'll be grabbing for the next Coke.
- Peter Rost, M.D. is a former VP of Pfizer and the author of Killer Drug and The Whistleblower.

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Caffeine does not work the same way heroin does. Caffeine is an antagonist of the adenosine receptors which indirectly stimulates the release of dopamine. Caffeine is a phenethylamine (like amphetamines), whereas heroin is an opiate (like morphine and codeine.) Heroin (and other opiates) acts similarly to the endorphins in our body - it stimulates the mu-opioid receptors. Endorphins cause dopamine to be released, so opiates do too.
Both cause a release of dopamine, but they don't act in the same way, at all. In order to work the same way, caffeine would need to be a painkiller, or heroin would need to be a stimulant.
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